Latest  Lab News:

01/25/2019: Hayden McSwiggin officially joined the Yan lab as a PhD student. Congrats and welcome! 

​​01/22/2018: A commentary on our motile cilia paper has come out! Thanks to Dr. Cheryl S. Rosenfeld for sharing her insights into the physiological functions of motile cilia.    

01/15/2019: Our paper on motile cilia of the efferent ducts is out! Thanks to our collaborators! This is a team work and it would not have been possible without collaborations. 

12/01/2018: Drs. Wei Yan and Neda Etezadi-Amoli received the 2019 UNR Med faculty development grant to study novel cell types identified in human Fallopian tube. 

07/01/2018: The Templeton Foundation funded a project entitled "Epigenetic Transgenerational Diagnostics for Disease Susceptibility". This project is led by Drs. Skinner (WSU), Yan (UNR), Holder (WSU) and Winchester (IU) and will be completed in 2021. 

06/01/2018: The Male Contraceptive Initiative funded our project entitled " Development of oral non-hormonal male contraceptives" for two years.  

05/01/2018: Our collaboration with Dr. Omid Khorram at Harbor-UCLA led to a paper entitled "Next-generation Sequencing Reveals Differentially Expressed Small Non-coding RNAs in Uterine Leiomyoma" published in Fertility and Sterility. Thanks to Dr. Ayman Al-Hendy for the nice commentary on this work
04/25/2018: Congrats to Qi Chen's lab! Their Dnmt2 paper finally came out in Nature Cell Biology. We are happy to be able to help with this project. 

04/25/2018: Dr. Yan won the 2018 SSR Research Award, which recognizes an active, regular member of the Society for outstanding research published over the previous six years. In making its recommendation, the Awards Committee considers the significance of the problems under investigation, the breadth and depth of the analyses performed, and the level of originality manifested in the publications of this work. 

04/22/2018: Dr. Yan delivered a talk entitled  “Environmental influences on sperm noncoding RNAs and subsequent fertilization and embryo development” in the 43rd Annual Conference of the American Society of Andrology (ASA), held on April 20-24, 2018, Portland, OR.  

03/31/2018: Dr. Yan was invited to attend the special conference commemorating the 30th anniversary of successful application of assisted reproductive technologies (ART) in mainland China, March 30-April 1, 2018, Beijing, China. The title of his talk was “Key Factors Affecting Transgenerational Epigenetic Inheritance”. 

03/28/2018: Dr. Yan visited the Center for Research on Reproduction and Women’s Health, and the Center for Germ Cell Research at the University of Pennsylvania Perelman School of Medicine. He gave a talk entitled “Role of m6A in spermatogenesis”.  

03/15/2018: Dr. Yan gave a talk entitled “Sperm RNA-mediated epigenetic inheritance” at the Center for Individualized Medicine, and Cancer Center and Center for Cell Signaling, the Mayo Clinic, Rochester, MN.

03/01/2018: The Male Contraceptive Initiative (MCI) awarded a grant ($150,000) to Dr. Yan in support of his research on a non-hormonal male contraceptive natural compound called SD-1

02/08/2018: A review papers authored by 16 leading experts on Developmental Origins of Health and Disease (DOHaD) was accepted for publication in Environmental International.

12/26/2017: Our paper entitled "ALKBH5-dependent m6A demethylation controls splicing and stability of long 3’UTR mRNAs in male germ cells" is published today in the Proceedings of the National Academy of Sciences USA. 

11/9/2017: Dr. Yan visited Dr. Jurrien Dean' lab at the NIDDK, and gave a seminar entitled "microRNAs as the master regulator of multi-ciliogenesis”.

10/30/2017: Dr. Yan was informed that he has been elected as a Fellow of the American Association for the Advancement of Science (AAAS).  He will attend the new Fellows induction ceremony, which will be held on February 17, 2018 during the AAAS annual meeting in Austin, TX.

08/31/2017: Our paper on "Microfluidics-based digital quantitative PCR for single cell small RNA quantification" is published! Congrats to Tian and Chong!

08/28/2017: Dr. Yan spoke in ​the 2nd joint meeting of Chinese Society of Animal Science and Chinese Society of Physiology, Hefei, China. The title of his talk: “microRNAs control mRNA fate by compartmentalization based on 3’UTR length in male germ cells”.    

07/01/2017: Drs. Wei Yan and Hugh Clarke officially become the Editors-in-Chief of Biology of Reproduction. Read their first editorial just published.

06/17/2017: Dr. Yan gave a talk entitled “Stable transgenerational inheritance of the kinky tail phenotype induced by a LINE1 insertion at Axin1 locus” at the Gordon Research Conference on Germinal Stem Cells and Epigenetic Inheritance, Hong Kong, China.

06/12/2017: Dr. Yan was invited as the distinguished speaker and gave a talk entitled “New insights into the functions of motile cilia in the reproductive tracts” in the Reproductive Science and Medicine Summit at Northwestern University, Chicago, IL.  

05/25/2017: Our paper entitled "MiRNAs control mRNA fate by compartmentalization based on 3’UTR length" has been accepted for publication in Genome Biology. Congrats to Clair, Chong and Tian! 

05/16/2017: Dr. Yan received the University of Nevada, Reno 2017 Outstanding Researcher Award at the University's Honor the Best Ceremony on May 16.

05/01/2017: Welcome to use our small RNA annotation software, AASRA!

04/21/2017: Tian Yu won the first prize in this year's 3MT@Nevada competition! Congrats, Tian! 

03/24/2017: Dr. Chuan He's recent Nature paperreporting that m6A controls mRNA turnover during maternal-to-zygotic transition in zebrafish is highlighted in Biology of Reproduction.  

02/21/2017: Our first paper with Dr. Joe Miano was accepted for publication in PNAS. In this work, we generated the LMOD1 KO mice using CRISPR/Cas9. 

11/14/2016: Our Miwi KO ROSI paper is online now.

10/2/2016: Drs. Chen, Yan and Duan's review on sperm RNA-mediated epigenetic inheritance has been published in Nature Reviews Genetics. It has generated >170 tweets, and >5,000 page views within 2 weeks!

09/28/2016: Dr. Yan delivered a talk in the 2016 International Conference of Physiological Sciences in Beijing. 

09/14/2016: Our SpermBase paper is published in Biology of Reproduction. Congrats to Andrew, Chong and other co-authors!

09/16/2016: Shuiqiao Yuan's Miwi ROSI paper has been accepted for publication in Environmental Epigenetics. Congrats!

08/23/2016: Dr. Yan acted as a discussion leader during the 2016 Gordon Research Conference on Mammalian Reproduction, Waterville Valley, NH.

07/25/2016: Tian Yu passed the qualifying exam and officially became a PhD candidate! Well done, Tian!

07/16/2016: Dr. Yan has been chosen by the Board of Directors of the Society for the Study of Reproduction (SSR) to be the next Editor-In-Chief of Biology of Reproduction, the official journal of the SSR. Congrats! 



Welcome to the Yan Lab!

We conduct exciting research to improve human reproductive health. 

— It is strange that only extraordinary people make the discoveries, which later appear so easy and simple. GEORG C. LICHTENBERG, 1742-1799

University of Nevada, Reno School of Medicine

University of Nevada, Reno School of Medicine